The novel paints a vivid picture of the Medici Papacy's grip on Florence, highlighting the stark contrast between the opulent lives of the ruling elite and the struggles of the common people. Rosa's heist becomes a thrilling act of rebellion against the corrupt Pope Leo X, who embodies the greed and abuse of power that fuels the citizens' resentment.

At its heart, 'Medici Heist' is a story about the power of teamwork and the bonds forged in the face of danger. Rosa carefully assembles a team of skilled misfits, each bringing unique talents and vulnerabilities to the table. As they navigate the complexities of the heist, their relationships are tested, and they learn to rely on each other for survival.

Set against the backdrop of Renaissance Florence, the novel seamlessly weaves in historical details and figures, including the iconic artist Michelangelo. The story cleverly uses art as a tool for deception, highlighting the era's fascination with beauty, illusion, and the pursuit of perfection. Rosa's understanding of art becomes a crucial asset in her elaborate plan, blurring the lines between reality and artifice.