Jessie's bravery and resolve are central to the story. Despite the overwhelming odds and the dangers she faces, her determination to save her friends and family drives her forward. This theme highlights the power of courage in the face of adversity and inspires readers to be resilient in their own lives.

The book raises important questions about the morality of using people as subjects in scientific experiments without their consent. The scientists' manipulation of the villagers' lives for the sake of observation is a critical commentary on ethical boundaries in research, making readers ponder the implications of such actions.

The juxtaposition of 1840s life with the modern world of 1996 creates a fascinating dynamic. This theme explores how people from different times perceive and adapt to technological and societal changes, offering a thought-provoking look at progress and its impact on human lives.