Hillary Rodham Clinton was inspired to write 'Something Lost, Something Gained' to share her personal experiences and the wisdom she has accumulated over the years. She wanted to provide readers with insights into her life, her resilience, and her ongoing activism, as well as to inspire others to make a positive impact in their own lives and communities.

In 'Something Lost, Something Gained,' Hillary Rodham Clinton addresses the theme of resilience by sharing stories of overcoming challenges and adapting to new roles and circumstances. She discusses moving past her presidential aspirations, engaging in new forms of activism, and demonstrating the power of resilience and the ability to reinvent oneself. This theme encourages readers to embrace change and persist in the face of adversity.

In 'Something Lost, Something Gained,' Hillary Rodham Clinton focuses on pressing global issues such as climate change, women's rights, and democracy. She shares her firsthand experiences working on these issues, from evacuating Afghan women to confronting climate change and supporting women dissidents. This theme highlights the importance of global awareness and activism, inspiring readers to take action on critical issues affecting the world.