The main concept explored in "Ghosts of My Life" is hauntology, a term coined by Jacques Derrida. Mark Fisher uses this concept to examine how contemporary society is haunted by the futures that never materialized, focusing on the cultural and social implications of these lost futures.

Mark Fisher addresses the theme of depression and melancholy by delving into his own experiences and those of others. He discusses how these emotional states are intertwined with the broader cultural and social context, shedding light on the personal struggles that often accompany the sense of lost futures.

In "Ghosts of My Life," Fisher analyzes a variety of cultural artifacts, including the works of David Peace, John Le Carré, Christopher Nolan, Joy Division, and Burial. He uses these examples to illustrate how they reflect and shape our understanding of the world, contributing to his broader critique of contemporary culture.